Titre : | BINDING AND KINETICS FOR MOLECULAR BIOLOGISTS |
Autre titre: | LIAISONS ET CINETIQUES POUR LA BIOLOGIE MOLECULAIRE |
Auteurs : | JAMES A. GOODRICH ; JENNIFER F. KUGEL |
Type de document : | Livre |
Editeur : | NEW YORK : COLD SPRING HARBOR LABORATORY PRESS, 2007 |
ISBN/ISSN/EAN : | 978-0-87969-736-5 |
Format : | 182 P. |
Note générale : | BIBLIOGR. P. 169-177. INDEX |
Langues: | Anglais |
Concepts : |
BIOLOGIE MOLECULAIRE
PROTEINE CINETIQUE ANALYSE DE DONNEES |
Résumé : | Binding and Kinetics for Molecular Biologsits offers a practical guide to the principles of quantitative analysis in biological experiments. The material is primarily aimed at working molecular biologists, but the scope and clarity of presentation make it equally suitable as an introduction for students. Topics covered range from the basics, such as measuring the concentrations of macromolecules, through considerations of binding constants and the kinetics of molecular interactions. The book ends with a thorough consideration of data analysis. Examples from the literature, and others newly created for the book, are used throughout to demonstrate how the principles described relate to real experimental models. Complimenting the material presented in the book is a collection of Web-based simulations that can be manipulated to visualize important concepts presented in the chapters. Table of Contents 1. Performing Quantitative Experiments with Biomolecules 2. Affinity Constants 3. Cooperativity in Binding 4. Rate Constants for Binding and Dissociation 5. Kinetics of Regulation and Cooperativity in Binding Reactions 6. Rate Constants for a Two-step Binding Reaction 7. Data Analysis Appendix 1 Equation Derivations Appendix 2 References and Resources Index |
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572.633 GOO | Livre | N - Nature | Disponible |