Résumé :
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Providing a detailed description of the relationship between protein structure, function, and dynamics, this book adopts an energy-oriented approach to discuss structural-biophysical aspects, molecular interactions, and thermodynamic changes that transpire in proteins. It presents the energetics of protein structure, guidelines to clarify protein action based on the structure-function relationship of protein-ligands, and the myriad functions of intrinsically unstructured proteins. The authors also describe current experimental and computational methods for studying structure and dynamics. The text includes various Internet-based resources, such as databases and algorithms, as well as applications to human disease, drug design, chemical warfare, and more.
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